abeo-HHC acetate
Acetic ester of a ring-expanded HHC; no published pharmacological data.
Harm-reduction warning
No characterised human dose: animal / in vitro data only. Effect profile, safety margin and acute toxicity are not documented in human clinical practice. Extremely potent compound: severe effects, seizures and deaths reported in the literature.
C₂₃H₃₄O₃
CID 177841621
- Family
- Semi-synthetic cannabinoidProvisional classification
- Molar mass
- 358.51 g/mol
Updated on
In plain terms
Abeo-HHC acetate is a laboratory molecule related to HHC, with one of its carbon rings holding one extra atom. It has not been described in hemp and has never been studied in animals or humans. Its only verifiable public trace is a record of chemical identifiers.
Receptors and activity
Pharmacology
Abeo-HHC acetate is a tricyclic chromene-type cannabinoid whose saturated carbon ring has seven atoms instead of six (a cyclohepta[c]chromene nucleus, hence the prefix abeo, which signals a rearranged skeleton), with a pentyl chain at position 3 and a phenol at position 1 esterified as an acetate. It resembles hexahydrocannabinol acetate (HHC-O), from which it differs by this ring size; HHC-O data cannot be transposed to it. No CB1 or CB2 affinity, no functional assay, no pharmacokinetic, metabolism or toxicity data have been published, and a Europe PMC search returns no article. No market report was found.
Key sources.
- PubChem, Abeo-HHC acetate, CID 177841621 (source: EPA DSSTox, DTXSID701359176) (new tab)
- Europe PMC, search for « abeo-HHC » and « abeo-hexahydrocannabinol »: 0 results (October 2026) (new tab)
- ANSM, decision of 6 February 2026 amending the list of substances classified as narcotics and the list of psychotropic substances (new tab)
- ANSM, consolidated list of substances classified as narcotics, updated 16 February 2026 (Annex III; Annex IV, « benzo[c]chromene » clause, HHC-O, HHCP) (new tab)
- ANSM, decision of 12 June 2023 amending the list of substances classified as narcotics (HHC, HHC-O, HHCP) (new tab)
History
- Source
- No presence in hemp is reported. The molecule is known only through its chemical identifiers (a PubChem record fed by the US Environmental Protection Agency's DSSTox database): no indexed publication describes it, and no market report or product analysis was found. How it is obtained could not be checked in a primary source.
Route of preparation
Chemical process
No known biosynthetic route. The prefix abeo signals a rearranged skeleton: the saturated carbon ring has seven atoms instead of six, and the phenol at position 1 is esterified as an acetate. The synthesis paper cited by secondary sources could not be consulted.
Legal framework
- European Union
No European Union text covers this molecule and no EUDA report was found. It is not in the schedules of the 1961 and 1971 United Nations conventions. Its status falls to the national law of each Member State.
- France
Abeo-HHC acetate is not listed by name on the French narcotics list (ANSM consolidated list of 16 February 2026), and its coverage by a generic entry is not established. The entry "Tetrahydrocannabinols, their esters, ethers, salts…", in annex III since the ANSM decision of 6 February 2026, covers tetrahydrocannabinols, which this ring-expanded, saturated molecule is not. The generic clause of annex IV (decisions of 22 May and 3 June 2024) covers derivatives of the benzo[c]chromene nucleus, including with an esterified hydroxyl at position 1; but this molecule's nucleus is a cyclohepta[c]chromene, and no published decision says whether this rearrangement takes it outside the clause. For reference, HHC, HHC acetate (HHC-O) and HHCP have been listed by name since the decision of 12 June 2023.
Sources: EUR-Lex, UNODC, CND, ANSM, IUPHAR/BPS, ChEBI, EUDA. Our method.
Classification
Family, origin and source verification
- Family
Semi-synthetic cannabinoid › Provisional classification
- Chemistry
C5 side chain · neutral form
- Verification
Checked on 20 October 2026; some points still await human review.
- Wikipedia (English)
Article paired by the molecule's structure (InChIKey), revision read on 19 October 2026. Read as a second opinion, never cited as a source.
References
- PubChem, Abeo-HHC acetate, CID 177841621 (source: EPA DSSTox, DTXSID701359176) (new tab)
- Europe PMC, search for « abeo-HHC » and « abeo-hexahydrocannabinol »: 0 results (October 2026) (new tab)
- ANSM, decision of 6 February 2026 amending the list of substances classified as narcotics and the list of psychotropic substances (new tab)
- ANSM, consolidated list of substances classified as narcotics, updated 16 February 2026 (Annex III; Annex IV, « benzo[c]chromene » clause, HHC-O, HHCP) (new tab)
- ANSM, decision of 12 June 2023 amending the list of substances classified as narcotics (HHC, HHC-O, HHCP) (new tab)
Identifiers
Names
- IUPAC name
- [(6aR,11aR)-6,6-dimethyl-3-pentyl-7,8,9,10,11,11a-hexahydro-6aH-cyclohepta[c]chromen-1-yl] acetate
Identifiers
- Formula
- C₂₃H₃₄O₃
- PubChem CID
- 177841621(new tab)
- InChIKey
- NTJCIGWEPIAFSM-RTBURBONSA-N
- SMILES
- CCCCCc1cc(OC(C)
= O) c2c(c1) OC(C) (C) [C@@H] 1CCCCC[C@@H] 21
LLM ingestion format: a structured superset of the entry (identifiers, binding, versioned legal status). Full corpus.