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abeo-HHC acetate

Acetic ester of a ring-expanded HHC; no published pharmacological data.

Level of detail

Harm-reduction warning

No characterised human dose: animal / in vitro data only. Effect profile, safety margin and acute toxicity are not documented in human clinical practice. Extremely potent compound: severe effects, seizures and deaths reported in the literature.

C₂₃H₃₄O₃

CID 177841621

Family
Semi-synthetic cannabinoidProvisional classification
Molar mass
358.51 g/mol

Updated on

In plain terms

Abeo-HHC acetate is a laboratory molecule related to HHC, with one of its carbon rings holding one extra atom. It has not been described in hemp and has never been studied in animals or humans. Its only verifiable public trace is a record of chemical identifiers.

Receptors and activity

    Bar length follows the measured value (Ki, Kd, EC50 or IC50), on one scale shared by every entry, from 100 µM to 0.1 nM. A target with no cited value has no bar.

    Pharmacology

    Abeo-HHC acetate is a tricyclic chromene-type cannabinoid whose saturated carbon ring has seven atoms instead of six (a cyclohepta[c]chromene nucleus, hence the prefix abeo, which signals a rearranged skeleton), with a pentyl chain at position 3 and a phenol at position 1 esterified as an acetate. It resembles hexahydrocannabinol acetate (HHC-O), from which it differs by this ring size; HHC-O data cannot be transposed to it. No CB1 or CB2 affinity, no functional assay, no pharmacokinetic, metabolism or toxicity data have been published, and a Europe PMC search returns no article. No market report was found.

    History

    Source
    No presence in hemp is reported. The molecule is known only through its chemical identifiers (a PubChem record fed by the US Environmental Protection Agency's DSSTox database): no indexed publication describes it, and no market report or product analysis was found. How it is obtained could not be checked in a primary source.

    Route of preparation

    Chemical process

    No known biosynthetic route. The prefix abeo signals a rearranged skeleton: the saturated carbon ring has seven atoms instead of six, and the phenol at position 1 is esterified as an acetate. The synthesis paper cited by secondary sources could not be consulted.

    Classification

    Family, origin and source verification

    Family

    Semi-synthetic cannabinoid › Provisional classification

    Chemistry

    C5 side chain · neutral form

    Verification

    Checked on 20 October 2026; some points still await human review.

    Wikipedia (English)

    Abeo-HHC acetate (new tab)

    Article paired by the molecule's structure (InChIKey), revision read on 19 October 2026. Read as a second opinion, never cited as a source.

    References

    Identifiers

    Names

    IUPAC name
    [(6aR,11aR)-6,6-dimethyl-3-pentyl-7,8,9,10,11,11a-hexahydro-6aH-cyclohepta[c]chromen-1-yl] acetate

    Identifiers

    Formula
    C₂₃H₃₄O₃
    InChIKey
    NTJCIGWEPIAFSM-RTBURBONSA-N
    SMILES
    CCCCCc1cc(OC(C)=O)c2c(c1)OC(C)(C)[C@@H]1CCCCC[C@@H]21

    Machine-readable entry (JSON)

    LLM ingestion format: a structured superset of the entry (identifiers, binding, versioned legal status). Full corpus.