CBND-C3Cannabinodivarin
The propyl homologue of cannabinodiol, reported once by GC-MS in 1972; never isolated, pharmacology not studied.
Harm-reduction warning
No characterised human dose: animal / in vitro data only. Effect profile, safety margin and acute toxicity are not documented in human clinical practice. Extremely potent compound: severe effects, seizures and deaths reported in the literature.
C₁₉H₂₂O₂
CAS 41408-26-8
- Family
- PhytocannabinoidMinor
- Origin
- Tentative identification
- Molar mass
- 282.40 g/mol
Updated on
In plain terms
Cannabinodivarin (CBND-C3) is a cannabinoid reported only once, in 1972, in hashish, and never isolated. It is the short-chain variant of cannabinodiol. How it forms and what it does in the body are unknown.
Receptors and activity
Pharmacology
CBND-C3 belongs to the CBND type, the smallest of the eleven phytocannabinoid types recorded by Radwan et al. (2021), which has only two members. Its sole mention rests on a GC-MS detection in hashish reported in 1972 at a symposium; it has never been isolated or confirmed against a standard, which makes it a tentative identification. Its C5 homologue, cannabinodiol, was by contrast isolated from Lebanese hashish, synthesised and chemically linked to cannabinol in 1977. No affinity, activity, pharmacokinetic or toxicity measurement was found for CBND-C3.
Key sources.
- Radwan et al. 2021, Molecules: CBND type (reference 41: van Ginneken et al. 1972, Elba GC-MS symposium) (new tab)PMID 34066753
- Lousberg et al. 1977, Phytochemistry 16:595: cannabinodiol (C5 homologue), identification and synthesis (new tab)DOI 10.1016/0031-9422(77)80023-X
- GSRS, UNII EWM4FP2BWD: cannabinodivarin (achiral, CAS 41408-26-8, PubChem 59444390) (new tab)
- ANSM, consolidated list of narcotics, updated 26/06/2026 (new tab)
History
- Source
- Hashish: tentative identification by GC-MS (1972), never isolated or confirmed against a standard; origin not established
Biosynthetic pathway
No formation pathway has been studied for CBND-C3. Its C5 homologue, cannabinodiol, was obtained from cannabinol (Radwan 2021); an analogous derivation from cannabivarin has not been demonstrated by any source.
Legal framework
- European Union
No EU instrument specific to the molecule. Not named in the schedules of the 1961 and 1971 United Nations conventions, according to annexes I to III of the ANSM consolidated list (26/06/2026). Checked 20/10/2026.
- France
Not a controlled drug: CBND-C3 is not named in the ANSM consolidated list (updated 26/06/2026) and, as a biphenyl molecule without a pyran ring, it does not belong to the generic class of benzo[c]chromene derivatives (ANSM decisions of 22/05/2024 and 03/06/2024). Checked 20/10/2026.
Sources: EUR-Lex, UNODC, CND, ANSM, IUPHAR/BPS, ChEBI, EUDA. Our method.
Classification
Family, origin and source verification
- Family
Phytocannabinoid › Minor
- Presence in the plant
Tentative identification, never isolated
- Chemistry
Type CBND · C3 side chain · neutral form
- Verification
Every fact on this entry was checked against its primary sources on 20 October 2026.
- Wikipedia (English)
No dedicated article.
References
- Radwan et al. 2021, Molecules: CBND type (reference 41: van Ginneken et al. 1972, Elba GC-MS symposium) (new tab)PMID 34066753
- Lousberg et al. 1977, Phytochemistry 16:595: cannabinodiol (C5 homologue), identification and synthesis (new tab)DOI 10.1016/0031-9422(77)80023-X
- GSRS, UNII EWM4FP2BWD: cannabinodivarin (achiral, CAS 41408-26-8, PubChem 59444390) (new tab)
- ANSM, consolidated list of narcotics, updated 26/06/2026 (new tab)
Identifiers
Names
- Common name
- Cannabinodivarin
- IUPAC name
- 2-(5-methyl-2-prop-1-en-2-ylphenyl)-5-propylbenzene-1,3-diol
- Other names
- CBVD · CBND-C3 · cannabinodivirin
Identifiers
- Formula
- C₁₉H₂₂O₂
- CAS
- 41408-26-8
- PubChem CID
- 59444390(new tab)
- InChIKey
- COURSARJQZMTEZ-UHFFFAOYSA-N
- SMILES
- CCCC1=
CC(= C(C(= C1) O) C2= C(C= CC(= C2) C) C(= C) C) O
LLM ingestion format: a structured superset of the entry (identifiers, binding, versioned legal status). Full corpus.