THCPTetrahydrocannabiphorol

Aliases.Tetrahydrocannabiphorol

Discovered in 2019 (Citti et al.). In vitro CB1 affinity up to 30× greater than THC.

Updated on 1 May 2026

Level of detail

Identifiers

Formula: C₂₃H₃₄O₂
CAS: 54763-99-4
PubChem CID: 6453074
First described: 2019 (Citti et al.)
Origin: Plant

In plain terms

THCP is a longer-chain THC, naturally ultra-rare, and roughly 30 times better at “catching” the CB1 receptor in laboratory assays. In use, the potency is not multiplied by 30 but remains marked - so it should be dosed with care.

Receptors and activity

CB1
Agonist
CB2
Partial agonist

Agonist
Partial agonist
Antagonist
Modulator
Inverse agonist

Hover over a row for the precise value (Ki, EC50…)

Subjective signature

Hover over an axis to read its definition.

Calm
45
Clarity
25
Sleep
70
Appetite
80
High
95

Editorial estimate, not clinical.

Pharmacology

Discovered in 2019 by Cinzia Citti's team at the University of Modena, THCP immediately intrigued the scientific community: its 7-carbon-long alkyl chain (instead of the 5 of THC) gives it a CB1 affinity up to 30 times greater than that of THC in in vitro binding assays. This does not mean that it is 30 times “stronger” in use: pharmacokinetics and oral bioavailability greatly moderate this theoretical potency. In the natural state, it exists at concentrations of the order of 0.01% - targeted extraction techniques are therefore needed to isolate it. THCP is not internationally scheduled as of May 2026 but remains subject to the 0.3% total THC threshold in any finished product marketed in the EU.