40% CBD oil: 16 to 20 mg per drop, the maths
A 40% CBD oil usually holds 4,000 mg of cannabidiol in a 10 ml bottle, which is 400 mg per millilitre. With a dropper giving 20 to 25 drops per millilitre, every drop contains 16 to 20 mg of CBD, eight to ten times EFSA's provisional reference for an entire day. Since May 2026, such an oil can no longer be sold in France for swallowing.

Key takeaways
- In most cases 40% stands for 400 mg of CBD per ml, which is 4,000 mg in 10 ml.
- A drop contains 16 to 20 mg, compared with 2 to 2.5 mg for a 5% oil.
- EFSA's reference is 2 mg a day for an adult of 70 kg; the UK Food Standards Agency uses 10 mg.
- Only 5 of 29 oils bought in the UK held the stated amount to within 10%.
- On 20 May 2026, France's agriculture ministry confirmed that CBD foods are not authorised.
What "40%" on a bottle means
The percentage is the proportion of CBD in the oil. Most sellers use 40% to mean 400 mg per millilitre, so 4,000 mg in 10 ml and 12,000 mg in 30 ml. The remainder is a carrier oil, often medium-chain triglycerides (MCT), olive oil or hemp seed oil.
The figure is still easy to misread, because a percentage can be by weight or by volume and labels rarely specify which. Divide the total in mg by the volume instead: 4,000 mg in 10 ml gives 400 mg/ml whichever way the percentage is expressed. When the label states no total in mg, "40%" is too vague for any precise calculation.
Look at the word "spectrum" as well. A full-spectrum oil retains the other hemp compounds, a little THC under the 0.30% limit among them, while an isolate-based oil contains CBD alone. The difference is explained in our definition of full spectrum and our comparison of full spectrum and isolate.
Table: mg of CBD per drop by strength
Everything depends on how big a drop is. According to the Food Standards Agency (FSA), the UK food regulator, 10 mg of CBD is about 4 to 5 drops of 5% oil. At 50 mg/ml for a 5% oil, that puts one drop at 2 to 2.5 mg and the dropper at 20 to 25 drops per millilitre. The table uses the same dropper for the other strengths.
| Strength | CBD per ml | CBD per drop | CBD in 10 ml |
|---|---|---|---|
| 5% | 50 mg | 2 to 2.5 mg | 500 mg |
| 10% | 100 mg | 4 to 5 mg | 1,000 mg |
| 20% | 200 mg | 8 to 10 mg | 2,000 mg |
| 30% | 300 mg | 12 to 15 mg | 3,000 mg |
| 40% | 400 mg | 16 to 20 mg | 4,000 mg |
These figures are estimates. The size of a drop varies with the dropper tip, the viscosity and temperature of the oil, and the angle of the bottle. At 40% the margin of error is large, since a slightly bigger drop adds several milligrams. A graduated syringe gives more precision: 0.1 ml of a 40% oil holds 40 mg of CBD, and 0.05 ml holds 20.
Why a single drop already exceeds official references
Two authorities give a figure for CBD in food. On 9 February 2026, EFSA set a provisional safe level of 0.0275 mg per kilo of body weight per day, roughly 2 mg for an adult of 70 kg. The level covers only CBD of at least 98% purity. The agency could not establish safety for people under 25, pregnant or breastfeeding women, or people taking medication. Since October 2023, the UK FSA has advised against going above 10 mg a day.
A single drop of 40% oil equals 8 to 10 times EFSA's daily reference and 1.6 to 2 times the FSA's. Staying at 2 mg would require a tenth of a drop, and no dropper delivers that. The format's practical limit lies there: with so much CBD in so little liquid, a small amount cannot be measured in drops. Our article on how much CBD per day explains the origin of these references.
None of these figures is a recommended dose. Epidyolex, the only authorised CBD medicine, is a 100 mg/ml solution prescribed under medical supervision for rare forms of epilepsy. A 40% oil is four times as concentrated and comes with none of those controls. CBD interacts with some medicines, so ask a doctor or a pharmacist if you are on any treatment.
What the bottle really contains
A high strength printed on the label is no guarantee of the contents. In 2023 a UK team tested 29 CBD oils bought in the UK. Only 5 held the stated amount to within 10%, 23 held less, and one held 50% more. In France, the addiction monitoring study run with Lille University Hospital looked at ten products bought in pharmacies, mostly oils, and found a CBD level matching the label in only one case out of two.
For an oil, three lines of a certificate of analysis matter. The first is the CBD concentration in mg/ml, which you compare with the stated total. The second is the Δ⁹-THC, capped at 0.30% of the product; at 0.2%, one gram of oil contains 2 mg of THC. The third is the batch number, which has to match your bottle. Our guide to reading a certificate of analysis goes through each line, and the measurement methods are described on the laboratory page.
The traces of THC in a full-spectrum oil can also count at the wheel. What these tests detect is explained in our guide to saliva drug tests.
The legal framework in 2026: no more oil to swallow
Bottled or in capsules, a CBD oil meant to be swallowed counts as a food. It comes under Regulation (EU) 2015/2283 on novel foods, which lets only authorised foods onto the market, and no CBD-based ingredient has been authorised.
France's agriculture ministry set out its position on 20 May 2026: foods containing CBD are not authorised, food supplements included, and checks now extend to every sales channel. Hemp seeds and their derivatives, such as hemp seed oil, are the only exception, provided they are not enriched with cannabinoids. The strength is irrelevant: a 5% oil to swallow is covered exactly as a 40% oil is.
An oil sold for the skin comes under another text, the EU cosmetics regulation, and may not be presented as something to swallow. The timeline is set out in our overview of CBD regulation in 2026. The oils in our catalogue are grouped in the CBD oils category; their stated strengths run from 5.1 to 19.6%, so none reaches 40%.
Frequently asked questions
Between 16 and 20 mg with a dropper giving 20 to 25 drops per millilitre, since a 40% oil holds 400 mg per ml. The actual size of a drop depends on the dropper tip and on how viscous the oil is.
Not in itself. The percentage measures how much CBD a given volume holds and says nothing about an effect. A drop of 40% oil contains as much CBD as four drops of 10% oil, and it is much harder to measure precisely.
About 4,000 mg, assuming the maker means 400 mg per ml. Look for the total in mg on the label and on the batch certificate of analysis, because that figure is what you need to work out the real concentration.
Not for swallowing. On 20 May 2026, France's agriculture ministry restated that CBD foods and supplements are not authorised under the novel food regulation. A cosmetic oil may not be presented as something to ingest.
If you mix two oils yourself, nothing verifies the resulting concentration, and the new bottle has no lab report. Choosing a lower strength when you buy makes measuring easier.
Written by the Phytogrammes team
Each journal article draws on cited primary sources: ANSM, EFSA, EUR-Lex and peer-reviewed publications. Product profiles are distinguished from documented laboratory results. Our approach.
Article published on . CBD is not a medicine.